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Spatial organization of enzymes to enhance synthetic pathways in microbial chassis: a systematic review
For years, microbes have been widely applied as chassis in the construction of synthetic metabolic pathways. However, the lack of in vivo enzyme clustering of heterologous metabolic pathways in these organisms often results in low local concentrations of enzymes and substrates, leading to a low prod...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066912/ https://www.ncbi.nlm.nih.gov/pubmed/30064437 http://dx.doi.org/10.1186/s12934-018-0965-0 |