Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline

BACKGROUND: Chromatin loops form a basic unit of interphase nuclear organization, with chromatin loop anchor points providing contacts between regulatory regions and promoters. However, the mutational landscape at these anchor points remains under-studied. Here, we describe the unusual patterns of s...

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Detalles Bibliográficos
Autores principales: Kaiser, Vera B., Semple, Colin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066925/
https://www.ncbi.nlm.nih.gov/pubmed/30060743
http://dx.doi.org/10.1186/s13059-018-1483-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066925/
https://www.ncbi.nlm.nih.gov/pubmed/30060743
http://dx.doi.org/10.1186/s13059-018-1483-4

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