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Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria

BACKGROUND: Most amino acids are encoded by multiple synonymous codons. However, synonymous codons are not used equally, and this biased codon use varies between different organisms. It has previously been shown that both selection acting to increase codon translational efficiency and selection acti...

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Detalles Bibliográficos
Autores principales: Seward, Emily A., Kelly, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066932/
https://www.ncbi.nlm.nih.gov/pubmed/30064467
http://dx.doi.org/10.1186/s13059-018-1480-7