Chronic Intermittent Hypoxia-Induced Vascular Dysfunction in Rats is Reverted by N-Acetylcysteine Supplementation and Arginase Inhibition

Chronic intermittent hypoxia (CIH), the main attribute of obstructive sleep apnea (OSA), produces oxidative stress, endothelial dysfunction, and hypertension. Nitric oxide (NO) plays a critical role in controlling the vasomotor tone. The NO level depends on the L-arginine level, which can be reduced...

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Detalles Bibliográficos
Autores principales: Krause, Bernardo J., Casanello, Paola, Dias, Ana C., Arias, Paulina, Velarde, Victoria, Arenas, German A., Preite, Marcelo D., Iturriaga, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066978/
https://www.ncbi.nlm.nih.gov/pubmed/30087615
http://dx.doi.org/10.3389/fphys.2018.00901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066978/
https://www.ncbi.nlm.nih.gov/pubmed/30087615
http://dx.doi.org/10.3389/fphys.2018.00901

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