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The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs

During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown. Our study showed that fully reprogrammed mature iPSCs or mouse embryonic stem cells exp...

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Detalles Bibliográficos
Autores principales: Liu, Qidong, Wang, Guiying, Lyu, Yao, Bai, Mingliang, Jiapaer, Zeyidan, Jia, Wenwen, Han, Tong, Weng, Rong, Yang, Yiwei, Yu, Yangyang, Kang, Jiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066996/
https://www.ncbi.nlm.nih.gov/pubmed/29910124
http://dx.doi.org/10.1016/j.stemcr.2018.05.008