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Polymorphism rs1052536 in Base Excision Repair Gene Is a Risk Factor in a High-Risk Area of Neural Tube Defects in China

BACKGROUND: DNA Base Excision Repair Gene-DNA LigaseIII (LIG3) is an important repair gene in the repair pathway and plays an important role in maintaining the integrity of mitochondria. Rs1052536 and rs3135967 polymorphisms of the gene are associated with lung cancer, keratoconus, and Fuchs endothe...

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Detalles Bibliográficos
Autores principales: Li, Guannan, Wang, Xin, Wang, Xiuwei, Guan, Zhen, Guo, Jin, Wang, Fang, Zhang, Jianzhao, Niu, Bo, Zhang, Ting, Wang, Jianhua, Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067017/
https://www.ncbi.nlm.nih.gov/pubmed/30022792
http://dx.doi.org/10.12659/MSM.907492