A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3

Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds, are extensively used as experimental tools to deliver CO, a biological ‘gasotransmitter’, in mammalian systems. CORMs are also explored as potential novel antimicrobial drugs, effectively and rapidly killing bacteria...

Descripción completa

Detalles Bibliográficos
Autores principales: Southam, Hannah M., Smith, Thomas W., Lyon, Rhiannon L., Liao, Chunyan, Trevitt, Clare R., Middlemiss, Laurence A., Cox, Francesca L., Chapman, Jonathan A., El-Khamisy, Sherif F., Hippler, Michael, Williamson, Michael P., Henderson, Peter J.F., Poole, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067063/
https://www.ncbi.nlm.nih.gov/pubmed/30007887
http://dx.doi.org/10.1016/j.redox.2018.06.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067063/
https://www.ncbi.nlm.nih.gov/pubmed/30007887
http://dx.doi.org/10.1016/j.redox.2018.06.008

Ejemplares similares