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Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and the I(h) current they generate contribute to the pathophysiological mechanisms of absence seizures (ASs), but their precise role in neocortical and thalamic neuronal populations, the main components of the network underlying AS g...
Autores principales: | David, François, Çarçak, Nihan, Furdan, Szabina, Onat, Filiz, Gould, Timothy, Mészáros, Ádám, Di Giovanni, Giuseppe, Hernández, Vivian M., Chan, C. Savio, Lőrincz, Magor L., Crunelli, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067077/ https://www.ncbi.nlm.nih.gov/pubmed/29925625 http://dx.doi.org/10.1523/JNEUROSCI.0896-17.2018 |
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