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OCIAD1 Controls Electron Transport Chain Complex I Activity to Regulate Energy Metabolism in Human Pluripotent Stem Cells

Pluripotent stem cells (PSCs) derive energy predominantly from glycolysis and not the energy-efficient oxidative phosphorylation (OXPHOS). Differentiation is initiated with energy metabolic shift from glycolysis to OXPHOS. We investigated the role of mitochondrial energy metabolism in human PSCs usi...

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Detalles Bibliográficos
Autores principales: Shetty, Deeti K., Kalamkar, Kaustubh P., Inamdar, Maneesha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067085/
https://www.ncbi.nlm.nih.gov/pubmed/29937147
http://dx.doi.org/10.1016/j.stemcr.2018.05.015