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TNFα inhibitors exacerbate Mycobacterium paratuberculosis infection in tissue culture: a rationale for poor response of patients with Crohn’s disease to current approved therapy

Background The role of Mycobacteriumavium subspecies paratuberculosis (MAP) in Crohn’s disease (CD) is increasingly accepted as evident by detection of the bacteria in the blood and intestinal tissue from patients with CD, and by supporting data from several open-label anti-MAP treatment studies. Tu...

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Detalles Bibliográficos
Autores principales: Qasem, Ahmad, Naser, Saleh A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067372/
https://www.ncbi.nlm.nih.gov/pubmed/30073091
http://dx.doi.org/10.1136/bmjgast-2018-000216