Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells

We show that a human pluripotent stem cell (hPSC) population cultured on a low-adhesion substrate developed two hPSC subtypes with different colony morphologies: flat and domed. Notably, the dome-like cells showed higher active proliferation capacity and increased several pluripotent genes’ expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Leqian, Li, Junjun, Hong, Jiayin, Takashima, Yasuhiro, Fujimoto, Nanae, Nakajima, Minako, Yamamoto, Akihisa, Dong, Xiaofeng, Dang, Yujiao, Hou, Yu, Yang, Wei, Minami, Itsunari, Okita, Keisuke, Tanaka, Motomu, Luo, Chunxiong, Tang, Fuchou, Chen, Yong, Tang, Chao, Kotera, Hidetoshi, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067523/
https://www.ncbi.nlm.nih.gov/pubmed/30008324
http://dx.doi.org/10.1016/j.stemcr.2018.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067523/
https://www.ncbi.nlm.nih.gov/pubmed/30008324
http://dx.doi.org/10.1016/j.stemcr.2018.06.003

Ejemplares similares