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Folic acid-conjugated mesoporous silica nanoparticles for enhanced therapeutic efficacy of topotecan in retina cancers

In this study, topotecan-loaded mesoporous silica nanoparticles were prepared and surface conjugated with folic acid (FTMN) to enhance the therapeutic efficacy of topotecan for the treatment of retinoblastoma (RB) cancers. The particles were nano-sized and exhibited a sustained release of drug in th...

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Detalles Bibliográficos
Autores principales: Qu, Wei, Meng, Bo, Yu, Yangyang, Wang, Shaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067616/
https://www.ncbi.nlm.nih.gov/pubmed/30100721
http://dx.doi.org/10.2147/IJN.S142668