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Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens

Aims: DsbA catalyzes disulfide bond formation in secreted and outer membrane proteins in bacteria. In pathogens, DsbA is a major facilitator of virulence constituting a target for antivirulence antimicrobial development. However, many pathogens encode multiple and diverse DsbA enzymes for virulence...

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Detalles Bibliográficos
Autores principales: Totsika, Makrina, Vagenas, Dimitrios, Paxman, Jason J., Wang, Geqing, Dhouib, Rabeb, Sharma, Pooja, Martin, Jennifer L, Scanlon, Martin J., Heras, Begoña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067686/
https://www.ncbi.nlm.nih.gov/pubmed/29237285
http://dx.doi.org/10.1089/ars.2017.7104