Serial counts of Mycobacterium tuberculosis in sputum as surrogate markers of the sterilising activity of rifampicin and pyrazinamide in treating pulmonary tuberculosis

BACKGROUND: Since the sterilising activity of new antituberculosis drugs is difficult to assess by conventional phase III studies, surrogate methods related to eventual relapse rates are required. METHODS: A suitable method is suggested by a retrospective analysis of viable counts of Mycobacterium t...

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Detalles Bibliográficos
Autores principales: Brindle, Richard, Odhiambo, Joseph, Mitchison, Denis
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60677/
https://www.ncbi.nlm.nih.gov/pubmed/11737875
http://dx.doi.org/10.1186/1471-2466-1-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60677/
https://www.ncbi.nlm.nih.gov/pubmed/11737875
http://dx.doi.org/10.1186/1471-2466-1-2

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