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Targeting the Mincle and TLR3 receptor using the dual agonist cationic adjuvant formulation 9 (CAF09) induces humoral and polyfunctional memory T cell responses in calves

There is a need for the rational design of safe and effective vaccines to protect against chronic bacterial pathogens such as Mycobacterium tuberculosis and Mycobacterium avium subsp. paratuberculosis in a number of species. One of the main challenges for vaccine development is the lack of safe adju...

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Detalles Bibliográficos
Autores principales: Thakur, Aneesh, Andrea, Athina, Mikkelsen, Heidi, Woodworth, Joshua S., Andersen, Peter, Jungersen, Gregers, Aagaard, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067743/
https://www.ncbi.nlm.nih.gov/pubmed/30063728
http://dx.doi.org/10.1371/journal.pone.0201253