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Rad51 recruitment and exclusion of non-homologous end joining during homologous recombination at a Tus/Ter mammalian replication fork barrier

Classical non-homologous end joining (C-NHEJ) and homologous recombination (HR) compete to repair mammalian chromosomal double strand breaks (DSBs). However, C-NHEJ has no impact on HR induced by DNA nicking enzymes. In this case, the replication fork is thought to convert the DNA nick into a one-en...

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Detalles Bibliográficos
Autores principales: Willis, Nicholas A., Panday, Arvind, Duffey, Erin E., Scully, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067765/
https://www.ncbi.nlm.nih.gov/pubmed/30024881
http://dx.doi.org/10.1371/journal.pgen.1007486