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Apolipoprotein(a) is the Product of a Pseudogene: Implications for the Pathophysiology of Lipoprotein(a)

Apolipoprotein(a) [apo(a)] is an apolipoprotein unique to lipoprotein(a) [Lp(a)]. Although it has no known function, Lp(a) is a risk factor for accelerated atherothrombosis. We hypothesize that LPA, the gene which encodes apo(a), is a heretofore unrecognized unprocessed pseudogene created by duplica...

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Detalles Bibliográficos
Autores principales: Sloop, Gregory D, Pop, Gheorghe, Weidman, Joseph J, St. Cyr, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067813/
https://www.ncbi.nlm.nih.gov/pubmed/30079281
http://dx.doi.org/10.7759/cureus.2715