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Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay
[Image: see text] Solute carriers (SLCs) are transmembrane proteins that transport various nutrients, metabolites, and drugs across cellular membranes. Despite the relevance of SLCs to cell homeostasis, metabolism, and disease states, for the majority of SLCs we lack experimental evidence regarding...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067815/ https://www.ncbi.nlm.nih.gov/pubmed/29851333 http://dx.doi.org/10.1021/acschembio.8b00270 |