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Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation

Autophagy is an essential physiological process that maintains cellular homeostasis by eliminating harmful protein aggregates, damaged organelles and certain pathogens through lysosomal degradation. During autophagy specialized structures, known as autophagosomes are formed that recruit the cargo th...

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Detalles Bibliográficos
Autores principales: Bansal, Megha, Moharir, Shivranjani C, Swarup, Ghanshyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067844/
https://www.ncbi.nlm.nih.gov/pubmed/30083281
http://dx.doi.org/10.1080/19420889.2018.1467189