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Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans

During development, neurons form synapses with their fate-determined targets. While we begin to elucidate the mechanisms by which extracellular ligand-receptor interactions enhance synapse specificity by inhibiting synaptogenesis, our knowledge about their intracellular mechanisms remains limited. H...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Shibata, Akihiro CE, Hendi, Ardalan, Kurashina, Mizuki, Fortes, Ethan, Weilinger, Nicholas L, MacVicar, Brian A, Murakoshi, Hideji, Mizumoto, Kota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067881/
https://www.ncbi.nlm.nih.gov/pubmed/30063210
http://dx.doi.org/10.7554/eLife.38801