Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice

Atoh1-null mice die at birth from respiratory failure, but the precise cause has remained elusive. Loss of Atoh1 from various components of the respiratory circuitry (e.g. the retrotrapezoid nucleus (RTN)) has so far produced at most 50% neonatal lethality. To identify other Atoh1-lineage neurons th...

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Detalles Bibliográficos
Autores principales: van der Heijden, Meike E, Zoghbi, Huda Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067883/
https://www.ncbi.nlm.nih.gov/pubmed/29972353
http://dx.doi.org/10.7554/eLife.38455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067883/
https://www.ncbi.nlm.nih.gov/pubmed/29972353
http://dx.doi.org/10.7554/eLife.38455

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