Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway

Oxidative stress is a critical factor in nonalcoholic fatty liver disease pathogenesis. MicroRNA-200a (miR-200a) is reported to target Kelch-like ECH-associated protein 1 (Keap1), which regulates nuclear factor erythroid 2-related factor 2 (Nrf2) anti-oxidant pathway. Polydatin (3,4′,5-trihydroxy-st...

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Detalles Bibliográficos
Autores principales: Zhao, Xiao-Juan, Yu, Han-Wen, Yang, Yan-Zi, Wu, Wen-Yuan, Chen, Tian-Yu, Jia, Ke-Ke, Kang, Lin-Lin, Jiao, Rui-Qing, Kong, Ling-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068203/
https://www.ncbi.nlm.nih.gov/pubmed/30014902
http://dx.doi.org/10.1016/j.redox.2018.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068203/
https://www.ncbi.nlm.nih.gov/pubmed/30014902
http://dx.doi.org/10.1016/j.redox.2018.07.002

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