Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression

Fumarase is an enzyme of the tricarboxylic acid (TCA) cycle in mitochondria, but in recent years, it has emerged as a participant in the response to DNA double strand breaks (DSBs) in the nucleus. In fact, this enzyme is dual-targeted and can be also readily detected in the mitochondrial and cytosol...

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Detalles Bibliográficos
Autores principales: Leshets, Michael, Silas, Yardena B. H., Lehming, Norbert, Pines, Ophry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068284/
https://www.ncbi.nlm.nih.gov/pubmed/30090811
http://dx.doi.org/10.3389/fmolb.2018.00068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068284/
https://www.ncbi.nlm.nih.gov/pubmed/30090811
http://dx.doi.org/10.3389/fmolb.2018.00068

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