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A combined tissue‐engineered/in silico signature tool patient stratification in lung cancer

Patient‐tailored therapy based on tumor drivers is promising for lung cancer treatment. For this, we combined in vitro tissue models with in silico analyses. Using individual cell lines with specific mutations, we demonstrate a generic and rapid stratification pipeline for targeted tumor therapy. We...

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Detalles Bibliográficos
Autores principales: Göttlich, Claudia, Kunz, Meik, Zapp, Cornelia, Nietzer, Sarah L., Walles, Heike, Dandekar, Thomas, Dandekar, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068345/
https://www.ncbi.nlm.nih.gov/pubmed/29797762
http://dx.doi.org/10.1002/1878-0261.12323