Epigenetic reactivation of LINE‐1 retrotransposon disrupts NuRD corepressor functions and induces oncogenic transformation in human bronchial epithelial cells

Long interspersed nuclear element‐1 (LINE‐1 or L1) reactivation is linked to poor prognosis in non‐small‐cell lung carcinoma (NSCLC), but the molecular bases of this response remain largely unknown. In this report, we show that challenge of human bronchial epithelial cells (HBECs) with the lung carc...

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Detalles Bibliográficos
Autores principales: Bojang, Pasano, Ramos, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068357/
https://www.ncbi.nlm.nih.gov/pubmed/29845737
http://dx.doi.org/10.1002/1878-0261.12329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068357/
https://www.ncbi.nlm.nih.gov/pubmed/29845737
http://dx.doi.org/10.1002/1878-0261.12329

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