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Construction of an Adenovirus Vaccine Expressing the Cross-reactive Antigen AMA1 for Neospora caninum and Toxoplasma gondii and Its Immune Response in an Animal Model

BACKGROUND: We aimed to construct an adenovirus expressing a cross-reactive fragment of the apical membrane antigen 1 (AMA1) antigen and evaluated the concomitant immune response in BABL/c mice, allowing protection against N. caninum and T. gondii infection. METHODS: The study was conducted in Agric...

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Detalles Bibliográficos
Autores principales: JIA, Lijun, GUO, Huanping, LIU, Mingming, GAO, Yang, ZHANG, Lei, LI, Hang, XIE, Suzhu, ZHANG, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068368/
https://www.ncbi.nlm.nih.gov/pubmed/30069207