Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission

Aged proteins can become hazardous to cellular function, by accumulating molecular damage. This implies that cells should preferentially rely on newly produced ones. We tested this hypothesis in cultured hippocampal neurons, focusing on synaptic transmission. We found that newly synthesized vesicle...

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Detalles Bibliográficos
Autores principales: Truckenbrodt, Sven, Viplav, Abhiyan, Jähne, Sebastian, Vogts, Angela, Denker, Annette, Wildhagen, Hanna, Fornasiero, Eugenio F, Rizzoli, Silvio O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068464/
https://www.ncbi.nlm.nih.gov/pubmed/29950309
http://dx.doi.org/10.15252/embj.201798044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068464/
https://www.ncbi.nlm.nih.gov/pubmed/29950309
http://dx.doi.org/10.15252/embj.201798044

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