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Analgesics promote welfare and sustain tumour growth in orthotopic 4T1 and B16 mouse cancer models

Murine orthotopic cancer models often require surgery, potentially causing pain or distress. However, analgesics are often withheld because they may alter tumour development. Two orthotopically implanted cancers were investigated in mice pre-treated with meloxicam (10 mg/kg), buprenorphine (0.2 mg/k...

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Detalles Bibliográficos
Autores principales: Lofgren, Jennifer, Miller, Amy L, Lee, Claudia Chui Shan, Bradshaw, Carla, Flecknell, Paul, Roughan, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068963/
https://www.ncbi.nlm.nih.gov/pubmed/29207902
http://dx.doi.org/10.1177/0023677217739934