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Analgesics promote welfare and sustain tumour growth in orthotopic 4T1 and B16 mouse cancer models
Murine orthotopic cancer models often require surgery, potentially causing pain or distress. However, analgesics are often withheld because they may alter tumour development. Two orthotopically implanted cancers were investigated in mice pre-treated with meloxicam (10 mg/kg), buprenorphine (0.2 mg/k...
Autores principales: | Lofgren, Jennifer, Miller, Amy L, Lee, Claudia Chui Shan, Bradshaw, Carla, Flecknell, Paul, Roughan, Johnny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068963/ https://www.ncbi.nlm.nih.gov/pubmed/29207902 http://dx.doi.org/10.1177/0023677217739934 |
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