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Nontypeable Haemophilus influenzae Lipooligosaccharide Expresses a Terminal Ketodeoxyoctanoate In Vivo, Which Can Be Used as a Target for Bactericidal Antibody

Nontypeable Haemophilus influenzae (NTHi) is an important pathogen in individuals of all ages. The lipooligosaccharide (LOS) of NTHi has evolved a complex structure that can be attributed to a multiplicity of glycosyltransferases, the random switching of glycosyltransferase gene expression via phase...

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Detalles Bibliográficos
Autores principales: Apicella, Michael A., Coffin, Jeremy, Ketterer, Margaret, Post, Deborah M. B., Day, Christopher J., Jen, Freda E.-C., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069110/
https://www.ncbi.nlm.nih.gov/pubmed/30065093
http://dx.doi.org/10.1128/mBio.01401-18