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Immunization by Replication-Competent Controlled Herpesvirus Vectors

Replication-competent controlled virus vectors were derived from the virulent herpes simplex virus 1 (HSV-1) wild-type strain 17syn+ by placing one or two replication-essential genes under the stringent control of a gene switch that is coactivated by heat and an antiprogestin. Upon activation of the...

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Detalles Bibliográficos
Autores principales: Bloom, David C., Tran, Robert K., Feller, Joyce, Voellmy, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069180/
https://www.ncbi.nlm.nih.gov/pubmed/29899091
http://dx.doi.org/10.1128/JVI.00616-18