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Immunization by Replication-Competent Controlled Herpesvirus Vectors
Replication-competent controlled virus vectors were derived from the virulent herpes simplex virus 1 (HSV-1) wild-type strain 17syn+ by placing one or two replication-essential genes under the stringent control of a gene switch that is coactivated by heat and an antiprogestin. Upon activation of the...
Autores principales: | Bloom, David C., Tran, Robert K., Feller, Joyce, Voellmy, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069180/ https://www.ncbi.nlm.nih.gov/pubmed/29899091 http://dx.doi.org/10.1128/JVI.00616-18 |
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