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Effect of valproic acid on survival in glioblastoma: A prospective single-arm study

BACKGROUND: Retrospective evidence suggests that valproic acid (VPA), an antiepileptic drug, is associated with improved outcomes in glioblastoma. The exact mechanism of interaction of VPA with radiation and temozolomide (TMZ) is still unclear. Laboratory studies show that VPA can enhance tumor cell...

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Detalles Bibliográficos
Autores principales: Valiyaveettil, Deepthi, Malik, Monica, Joseph, Deepa M., Ahmed, Syed Fayaz, Kothwal, Syed Akram, Vijayasaradhi, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069328/
https://www.ncbi.nlm.nih.gov/pubmed/30112328
http://dx.doi.org/10.4103/sajc.sajc_188_17