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Genistein and Myd88 Activate Autophagy in High Glucose-Induced Renal Podocytes In Vitro

BACKGROUND: Renal podocyte damage plays a crucial role in the development of diabetic nephropathy. Genistein is derived from a leguminous plant, and MyD88 and TRIF are adaptor molecules in the Toll-like receptor (TLR) signaling pathway, which may play a role in autophagy. In this study, we utilized...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Li, Ying, Zhang, Tao, Chi, Yanqing, Liu, Maodong, Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069420/
https://www.ncbi.nlm.nih.gov/pubmed/29999001
http://dx.doi.org/10.12659/MSM.910868