Cargando…

Genistein and Myd88 Activate Autophagy in High Glucose-Induced Renal Podocytes In Vitro

BACKGROUND: Renal podocyte damage plays a crucial role in the development of diabetic nephropathy. Genistein is derived from a leguminous plant, and MyD88 and TRIF are adaptor molecules in the Toll-like receptor (TLR) signaling pathway, which may play a role in autophagy. In this study, we utilized...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yuanyuan, Li, Ying, Zhang, Tao, Chi, Yanqing, Liu, Maodong, Liu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069420/ https://www.ncbi.nlm.nih.gov/pubmed/29999001 http://dx.doi.org/10.12659/MSM.910868

Ejemplares similares

Salidroside Reduces High-Glucose-Induced Podocyte Apoptosis and Oxidative Stress via Upregulating Heme Oxygenase-1 (HO-1) Expression
por: Lu, Hua, et al.
Publicado: (2017)

Pyridoxamine Treatment of HK-2 Human Proximal Tubular Epithelial Cells Reduces Oxidative Stress and the Inhibition of Autophagy Induced by High Glucose Levels
por: Wang, Ying, et al.
Publicado: (2019)

MicroRNA-149 Suppresses Inflammation in Nucleus Pulposus Cells of Intervertebral Discs by Regulating MyD88
por: Qin, Chuqiang, et al.
Publicado: (2019)

Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis
por: Zhang, Tao, et al.
Publicado: (2019)

Protective Effect of Hesperidin Against Sepsis-Induced Lung Injury by Inducing the Heat-Stable Protein 70 (Hsp70)/Toll-Like Receptor 4 (TLR4)/ Myeloid Differentiation Primary Response 88 (MyD88) Pathway
por: Yuan, Xiaoyan, et al.
Publicado: (2019)

Gasdermin D Influence Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway
por: Li, Huifang, et al.
Publicado: (2021)

Interleukin 37 (IL-37) Reduces High Glucose-Induced Inflammation, Oxidative Stress, and Apoptosis of Podocytes by Inhibiting the STAT3–Cyclophilin A (CypA) Signaling Pathway
por: Zhang, Xiaobo, et al.
Publicado: (2020)

Autophagy Induced by Oxygen-Glucose Deprivation Mediates the Injury to the Neurovascular Unit
por: Zhang, Xinyang, et al.
Publicado: (2019)

Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes
por: Kang, Yingli, et al.
Publicado: (2019)

β-Arrestin 1/2 Aggravates Podocyte Apoptosis of Diabetic Nephropathy via Wnt/β-Catenin Pathway
por: Wang, Yao, et al.
Publicado: (2018)

Gremlin Regulates Podocyte Apoptosis via Transforming Growth Factor-β (TGF-β) Pathway in Diabetic Nephropathy
por: Wang, Xiao-Bing, et al.
Publicado: (2018)

Overexpression of Linc 4930556M19Rik Suppresses High Glucose-Triggered Podocyte Apoptosis, Fibrosis and Inflammation via the miR-27a-3p/Metalloproteinase 3 (TIMP3) Axis in Diabetic Nephropathy
por: Fan, Hong, et al.
Publicado: (2020)

CD36 Promotes Podocyte Apoptosis by Activating the Pyrin Domain-Containing-3 (NLRP3) Inflammasome in Primary Nephrotic Syndrome
por: Yang, Xuejun, et al.
Publicado: (2018)

Autophagy Inhibition Sensitizes Renal Tubular Epithelial Cell to G1 Arrest Induced by Transforming Growth Factor beta (TGF-β)
por: Yang, Chen, et al.
Publicado: (2020)

Usnic Acid Induces Cycle Arrest, Apoptosis, and Autophagy in Gastric Cancer Cells In Vitro and In Vivo
por: Geng, Xiaoge, et al.
Publicado: (2018)

MicroRNA-181a Regulates Apoptosis and Autophagy Process in Parkinson’s Disease by Inhibiting p38 Mitogen-Activated Protein Kinase (MAPK)/c-Jun N-Terminal Kinases (JNK) Signaling Pathways
por: Liu, Ying, et al.
Publicado: (2017)

Neutrophil Gelatinase-Associated Lipocalin Attenuates Ischemia/Reperfusion Injury in an In Vitro Model via Autophagy Activation
por: Yan, Cai, et al.
Publicado: (2018)

5-Hydroxy-4′-Nitro-7-Propionyloxy-Genistein Inhibited Invasion and Metastasis via Inactivating Wnt/β-Catenin Signal Pathway in Human Endometrial Carcinoma Ji Endometrial Cells
por: Bai, Jun, et al.
Publicado: (2018)

Antitumor Activity of Asiaticoside Against Multiple Myeloma Drug-Resistant Cancer Cells Is Mediated by Autophagy Induction, Activation of Effector Caspases, and Inhibition of Cell Migration, Invasion, and STAT-3 Signaling Pathway
por: Yingchun, Li, et al.
Publicado: (2019)

Role of Hypoxia-Inducible Factors 1α (HIF1α) in SH-SY5Y Cell Autophagy Induced by Oxygen-Glucose Deprivation
por: Niu, Guohui, et al.
Publicado: (2018)

Essential Oil from Fructus Alpiniae Zerumbet Protects Human Umbilical Vein Endothelial Cells In Vitro from Injury Induced by High Glucose Levels by Suppressing Nuclear Transcription Factor-Kappa B Signaling
por: Huang, Niwen, et al.
Publicado: (2017)

Myoglobin Mediates Autophagy of NRK-52E in Rat Renal Tubular Epithelial Cells Via the Pink1/Parkin Signaling Pathway
por: Chen, Zhiguo, et al.
Publicado: (2020)

The Role of Glucose Concentration and Resveratrol in Modulating Neuroinflammatory Cytokines: Insights from an In Vitro Blood–Brain Barrier Model
por: Komorowska, Justyna, et al.
Publicado: (2023)

Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy
por: Zhang, Zaiwei, et al.
Publicado: (2017)

Obestatin Plays Beneficial Role in Cardiomyocyte Injury Induced by Ischemia-Reperfusion In Vivo and In Vitro
por: Zhang, Qin, et al.
Publicado: (2017)

17β-Estradiol Promotes Angiogenesis of Rat Cardiac Microvascular Endothelial Cells In Vitro
por: Liu, HaiTao, et al.
Publicado: (2018)

Effects of High-Glucose and High-Fat Condition on Estrogen Receptor- and Sexual Precocity-Related Genes in GT1-7 Cells
por: Wang, Shuqin, et al.
Publicado: (2020)

Taxol-Resistant Gene 1 (Txr1) Mediates Oxaliplatin Resistance by Inducing Autophagy in Human Nasopharyngeal Carcinoma Cells
por: Chi, Hua-ming, et al.
Publicado: (2019)

Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells in Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway
por: Li, Chao, et al.
Publicado: (2019)

Role of B and T Lymphocyte Attenuator in Renal Transplant Recipients with Biopsy-Proven Acute Rejection
por: Wang, Zijie, et al.
Publicado: (2018)

Aberrant Methylation of PCDH8 is a Potential Prognostic Biomarker for Patients with Clear Cell Renal Cell Carcinoma
por: Lin, Ying-Li, et al.
Publicado: (2014)

Oncogenic Activity of Wrap53 in Human Colorectal Cancer In Vitro and in Nude Mouse Xenografts
por: Zhu, Yu, et al.
Publicado: (2018)

Comparative Evaluation of Two Antioxidants on Reversing the Immediate Bond Strength of Bleached Enamel: In Vitro Study
por: Zhang, Hong, et al.
Publicado: (2020)

Toxic Effects of Levofloxacin on Rat Annulus Fibrosus Cells: An In-vitro Study
por: Bai, Zhi-Long, et al.
Publicado: (2014)

Pancratistatin Inhibits the Growth of Colorectal Cancer Cells by Inducing Apoptosis, Autophagy, and G2/M Cell Cycle Arrest
por: Xiong, Yong, et al.
Publicado: (2019)

Apigenin Protects Against Renal Tubular Epithelial Cell Injury and Oxidative Stress by High Glucose via Regulation of NF-E2-Related Factor 2 (Nrf2) Pathway
por: Zhang, Jichen, et al.
Publicado: (2019)

Zafirlukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Reduces the Effect of Advanced Glycation End-Products in Rat Renal Mesangial Cells In Vitro
por: Yan, Liping, et al.
Publicado: (2019)

Exosomes from MiR-21-5p-Increased Neurons Play a Role in Neuroprotection by Suppressing Rab11a-Mediated Neuronal Autophagy In Vitro After Traumatic Brain Injury
por: Li, Dai, et al.
Publicado: (2019)

CircKIAA0907 Retards Cell Growth, Cell Cycle, and Autophagy of Gastric Cancer In Vitro and Inhibits Tumorigenesis In Vivo via the miR-452-5p/KAT6B Axis
por: Zhu, Lingyu, et al.
Publicado: (2020)

Diagnostic Value of Synovial Fluid Biomarkers for Periprosthetic Joint Infection: A Prospective, Double-blind Trial
por: Xu, Ying, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4auh8hss77duhlmql5ujd1b5gm