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Protective Effect of Dexmedetomidine on Endotoxin-Induced Acute Lung Injury in Rats

BACKGROUND: The purpose of this study was to investigate whether DEX exerts protective mechanisms in rats with acute lung injury (ALI) induced by the endotoxin lipopolysaccharide (LPS). The mortality rate of ALI is extremely high. DEX, an α(2) adrenergic receptor agonist, has potent anti-inflammator...

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Detalles Bibliográficos
Autores principales: Meng, Peng Z., Liu, Jing, Hu, Ping S., Tong, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069535/
https://www.ncbi.nlm.nih.gov/pubmed/30006502
http://dx.doi.org/10.12659/MSM.908887