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Ligustilide Ameliorates Memory Deficiency in APP/PS1 Transgenic Mice via Restoring Mitochondrial Dysfunction

Ligustilide, the main lipophilic component of Radix angelicae sinensis, has been shown to ameliorate cognitive dysfunction in a few Alzheimer's disease mouse models, but its mechanism is not fully understood. In this study, we employed 7-month-old APP/PS1 mice to explore whether LIG is able to...

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Detalles Bibliográficos
Autores principales: Xu, Yi-Jun, Mei, Yu, Qu, Zi-Ling, Zhang, Shi-Jie, Zhao, Wei, Fang, Jian-Song, Wu, Jun, Yang, Cong, Liu, Si-Jun, Fang, Yong-Qi, Wang, Qi, Zhang, Yong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069587/
https://www.ncbi.nlm.nih.gov/pubmed/30079347
http://dx.doi.org/10.1155/2018/4606752