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Helper-free Production of Laboratory Grade AAV and Purification by Iodixanol Density Gradient Centrifugation

Adeno-associated virus (AAV) is one of the most promising gene therapy vectors and is widely used as a gene delivery vehicle for basic research. As AAV continues to become the vector of choice, it is increasingly important for new researchers to have access to a simplified production and purificatio...

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Detalles Bibliográficos
Autores principales: Crosson, Sean M., Dib, Peter, Smith, J. Kennon, Zolotukhin, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069679/
https://www.ncbi.nlm.nih.gov/pubmed/30073177
http://dx.doi.org/10.1016/j.omtm.2018.05.001