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Helper-free Production of Laboratory Grade AAV and Purification by Iodixanol Density Gradient Centrifugation
Adeno-associated virus (AAV) is one of the most promising gene therapy vectors and is widely used as a gene delivery vehicle for basic research. As AAV continues to become the vector of choice, it is increasingly important for new researchers to have access to a simplified production and purificatio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069679/ https://www.ncbi.nlm.nih.gov/pubmed/30073177 http://dx.doi.org/10.1016/j.omtm.2018.05.001 |