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PDZD8 is not the ‘functional ortholog’ of Mmm1, it is a paralog

Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells. However, identifying PDZD8 as a “functional ortholog” of yeast Mmm1 (maintenance of mitochondrial morpholog...

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Detalles Bibliográficos
Autores principales: Wideman, Jeremy G., Balacco, Dario L., Fieblinger, Tim, Richards, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069729/
https://www.ncbi.nlm.nih.gov/pubmed/30109028
http://dx.doi.org/10.12688/f1000research.15523.1