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HiCcompare: an R-package for joint normalization and comparison of HI-C datasets

BACKGROUND: Changes in spatial chromatin interactions are now emerging as a unifying mechanism orchestrating the regulation of gene expression. Hi-C sequencing technology allows insight into chromatin interactions on a genome-wide scale. However, Hi-C data contains many DNA sequence- and technology-...

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Detalles Bibliográficos
Autores principales: Stansfield, John C., Cresswell, Kellen G., Vladimirov, Vladimir I., Dozmorov, Mikhail G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069782/
https://www.ncbi.nlm.nih.gov/pubmed/30064362
http://dx.doi.org/10.1186/s12859-018-2288-x