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MicroRNA-101 inhibits the expression of Rhes, a striatal-enriched small G-protein, at the post-transcriptional level in vitro

OBJECTIVE: Ras homolog enriched in striatum (Rhes) is a small GTP-binding protein that is predominantly localized in the striatal region of the brain. Rhes affects various signaling pathways and plays important roles in Huntington’s disease development caused by striatal anomalies. However, the mech...

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Detalles Bibliográficos
Autores principales: Mizuno, Hideya, Taketomi, Ayako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069827/
https://www.ncbi.nlm.nih.gov/pubmed/30064488
http://dx.doi.org/10.1186/s13104-018-3654-5