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Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models

Parkinson disease (PD) is the second most common neurodegenerative disorder after Alzheimer disease and is caused by genetics, environmental factors and aging, with few treatments currently available. Apoptosis and macroautophagy/autophagy play critical roles in PD pathogenesis; as such, modulating...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Liu, Weijin, Lu, Yongquan, Tian, Hao, Duan, Chunli, Lu, Lingling, Gao, Ge, Wu, Xia, Wang, Xiaomin, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070010/
https://www.ncbi.nlm.nih.gov/pubmed/29433359
http://dx.doi.org/10.1080/15548627.2017.1390636