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Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models
Parkinson disease (PD) is the second most common neurodegenerative disorder after Alzheimer disease and is caused by genetics, environmental factors and aging, with few treatments currently available. Apoptosis and macroautophagy/autophagy play critical roles in PD pathogenesis; as such, modulating...
Autores principales: | Liu, Jia, Liu, Weijin, Lu, Yongquan, Tian, Hao, Duan, Chunli, Lu, Lingling, Gao, Ge, Wu, Xia, Wang, Xiaomin, Yang, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070010/ https://www.ncbi.nlm.nih.gov/pubmed/29433359 http://dx.doi.org/10.1080/15548627.2017.1390636 |
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