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Isoflurane but Not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression?

BACKGROUND: The volatile anesthetic isoflurane may exert a rapid and long-lasting antidepressant effect in patients with medication-resistant depression. The mechanism underlying the putative therapeutic actions of the anesthetic have been attributed to its ability to elicit cortical burst suppressi...

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Detalles Bibliográficos
Autores principales: Brown, P Leon, Zanos, Panos, Wang, Leiming, Elmer, Greg I, Gould, Todd D, Shepard, Paul D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070045/
https://www.ncbi.nlm.nih.gov/pubmed/29554264
http://dx.doi.org/10.1093/ijnp/pyy029