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Matrine Exerts Antidepressant-Like Effects on Mice: Role of the Hippocampal PI3K/Akt/mTOR Signaling

BACKGROUND: Current antidepressants in clinical use always take weeks or even months to exert full therapeutic effects, and sometimes have serious side effects. Thus, it is very necessary to develop novel antidepressants with better efficacy and fewer adverse effects. The present study focused on in...

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Detalles Bibliográficos
Autores principales: Wu, Zhonghua, You, Zhengchen, Chen, Peng, Chen, Cheng, Chen, Fei, Shen, Jianhong, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070064/
https://www.ncbi.nlm.nih.gov/pubmed/29668939
http://dx.doi.org/10.1093/ijnp/pyy028