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Dysregulation of NF-kB in glandular epithelial cells results in Sjögren’s-like features
The autoimmune disease primary Sjögren’s syndrome (pSS) is characterized by hypofunction of the salivary glands (SGs), the cause of which is not correlated to lymphocytic SG infiltration, as prevailing dogma often states. We knocked out the NF-κB proinflammatory pathway inhibitor A20 in keratin14(+)...
Autores principales: | Wang, Xiaoyan, Shaalan, Abeer, Liefers, Silvia, Coudenys, Julie, Elewaut, Dirk, Proctor, Gordon B., Bootsma, Hendrika, Kroese, Frans G. M., Pringle, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070175/ https://www.ncbi.nlm.nih.gov/pubmed/30067782 http://dx.doi.org/10.1371/journal.pone.0200212 |
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