Matrix metalloproteinase promotes elastic fiber degradation in ligamentum flavum degeneration

Ligamentum flavum (LF) hypertrophy in lumbar spinal canal stenosis (LSCS) is characterized by a loss of elastic fibers and fibrosis. Chronic inflammation is thought to be responsible for the histological change but the mechanism underlying elastic fiber degradation remains unclear. Given that matrix...

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Detalles Bibliográficos
Autores principales: Sugimoto, Kazuki, Nakamura, Takayuki, Tokunaga, Takuya, Uehara, Yusuke, Okada, Tatsuya, Taniwaki, Takuya, Fujimoto, Toru, Mizuta, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070248/
https://www.ncbi.nlm.nih.gov/pubmed/30067795
http://dx.doi.org/10.1371/journal.pone.0200872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070248/
https://www.ncbi.nlm.nih.gov/pubmed/30067795
http://dx.doi.org/10.1371/journal.pone.0200872

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