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Retrograde axonal transport of rabies virus is unaffected by interferon treatment but blocked by emetine locally in axons
Neuroinvasive viruses, such as alpha herpesviruses (αHV) and rabies virus (RABV), initially infect peripheral tissues, followed by invasion of the innervating axon termini. Virus particles must undergo long distance retrograde axonal transport to reach the neuron cell bodies in the peripheral or cen...
Autores principales: | MacGibeny, Margaret A., Koyuncu, Orkide O., Wirblich, Christoph, Schnell, Matthias J., Enquist, Lynn W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070286/ https://www.ncbi.nlm.nih.gov/pubmed/30028873 http://dx.doi.org/10.1371/journal.ppat.1007188 |
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