Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during Drosophila development

Upstream open reading frames (uORFs) play important roles in regulating the main coding DNA sequences (CDSs) via translational repression. Despite their prevalence in the genomes, uORFs are overall discriminated against by natural selection. However, it remains unclear why in the genomes there are s...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Dou, Shengqian, He, Feng, Luo, Junjie, Wei, Liping, Lu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070289/
https://www.ncbi.nlm.nih.gov/pubmed/30028832
http://dx.doi.org/10.1371/journal.pbio.2003903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070289/
https://www.ncbi.nlm.nih.gov/pubmed/30028832
http://dx.doi.org/10.1371/journal.pbio.2003903

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