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Exploration and stabilization of Ras1 mating zone: A mechanism with positive and negative feedbacks

In mating fission yeast cells, sensing and response to extracellular pheromone concentrations occurs through an exploratory Cdc42 patch that stochastically samples the cell cortex before stabilizing towards a mating partner. Active Ras1 (Ras1-GTP), an upstream regulator of Cdc42, and Gap1, the GTPas...

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Detalles Bibliográficos
Autores principales: Khalili, Bita, Merlini, Laura, Vincenzetti, Vincent, Martin, Sophie G., Vavylonis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070293/
https://www.ncbi.nlm.nih.gov/pubmed/30028833
http://dx.doi.org/10.1371/journal.pcbi.1006317